Overview Decentralized Scienc… its own ecosystem listing on 1127 September 2026 and, unchanged since 11 September and across that rebrand. It raised…her than fusing it into one. The homepage also links three case studies, read on 27 September 2026, and between them they show how Bio's launch terms have changed. The HairDAO case study (https://www.bio.xyz/case-study/hairdao) , dated to HairDAO (/wiki/desci/ecosystem/hairdao) 's launch in the first cohort in November 2021, describes an open auction in which buyers set the clearing price and no valuation was fixed in advance. It sets that against today's Ignition Sales, which open at a fixed fully diluted valuation, “currently in a $2M to $3M band”, against a raise size agreed before the sale. The ARTAN Bio case study (https://www.bio.xyz/case-study/artan-bio) shows the IP-NFT (/wiki/desci/ip-nfts) route: $91,000 on a community vote in July 2023, the IP-NFT tokenized into five million tokens, a fifth of them sold for $300,000 in June 2024, and the IP itself kept by the company, so holders get a vote on the research rather than ownership of it. The PeptAI case study (https://www.bio.xyz/case-study/peptai) covers the first launch on Bio's coin-to-company framework, a $50,000 raise in May 2026 whose governance token has a stated route to convert into equity; Bio, which built PeptAI (/wiki/desci/ecosystem/peptai) in-house, reports $112,000 of trading fees paid to the project since. That is three ownership structures from one launchpad: a DAO that owns its patents, a company that owns its IP, and a token meant to become equity. Relevance to Radix Radix's a… (/wiki/desci/desci-funding) .

Overview Decentralized Scienc…oulbound vote tokens – minted at 0.01 per XRD of gross value on aonly buy as well as 1 per rankedranked ballots, one per ballot, so a backer who never votes still qualifieshas bought but never voted has no exit to take – letting contributors who lo…eight that decides a vote, so aof two backer who bought and voteds holding the same tokens, the one who has voted on more proposals redeems more of the treasury,thand one who only bought the same tokensredeems nothing through exit at all. It's the same “community fun… (/wiki/desci/desci-funding) .

Overview Decentralized Scienc…i/ecosystem/bio-xyz) — which describes itself as “DeSci's new financial layer” — nits documentation (https://docs.bio.xyz/) still calls “a new financial layer for funding and developing early-stage biotech”, wording its homepage dropped in the rebrand described below — coordinates ten BioDAOs (https://www.bio.xyz/) , recounted off its own ecosystem listing on 15 August 2026, having1 September 2026 and unchanged across that rebrand. It raised over $33M in its BIO Genesis (https://www.bio.xyz/) round –, Binance Labs' first DeSci investment, in November 2024, – both figures dated on Bio'sa published timeline Bio has since removed from its site, and read here off the Internet Archive’s 21 August 2026 capture (http://web.archive.org/web/20260821150233/https://www.bio.xyz/) . The ten span longevity ( Vit…o eleventh. Bio has meanwhile fronted three further surfaces onrebuilt its homepage (https://www.bio.xyz/) around three further surfaces — Buildspace (https://buildsp…BIOS, an AI research assistant — retitling it “Science for the Network Age” and retiring both the “Gateway Drug to Decentralized Science” hero and the word “bioDAO”, which now appears nowhere on the page. The Internet Archive’s most recent capture, 21 August 2026, still holds the old homepage, so the redesign landed in the three weeks after it; none of Bio’s blog posts (https://www.bio.xyz/blog) announces it. The direction is the one to … (/wiki/desci/desci-funding) .

Overview Decentralized Scienc…berlin/) it launched OpenLabs —, backed by a fresh $6.9 milli…ed-decentralised-ai-platform) — pairing AI-assisted project development with community funding votes in a single interface — the same launcher that issues Bio's BioAgents (/wiki/desci/ecosystem/peptai) — a sign that. Read on 9 September 2026, openlabs.bio.xyz (https://openlabs.bio.xyz) is not the funding surface press coverage implied: it bills itself as “Where Scientists & AI Agents Discover Breakthroughs” and invites researchers to “post hypotheses, challenge ideas through peer review, and collaborate with researchers and AI agents”. Funding still happens somewhere else — on app.bio.xyz/launchpad (https://app.bio.xyz/launchpad) , which on the same date carries links to exactly the ten BioDAOs above and no eleventh. Bio has meanwhile fronted three further surfaces on its homepage (https://www.bio.xyz/) — Buildspace (https://buildspace.bio.xyz) for getting a project funding-ready, Biofy (https://biofy.xyz) for shipping products, and BIOS, an AI research assistant. The direction is the one to note: DeSci's frontier is moving fr…izing IP toward operating the full research workflow on-chainitself, and it is doing so by splitting the workflow across surfaces rather than fusing it into one. Relevance to Radix Radix's… an IP acquisition — with a pro-rataarticipation-weighted exit (/wiki/governance/voting…e rather than being locked in. That share is not a flat slice by balance: exit prices the treasury payout with the same (t·v)/(V·T) canonical weight that decides a vote, so a backer who bought and voted redeems more of the treasury than one who only bought the same tokens. It's the same “community fund… (/wiki/desci/desci-funding) .

Overview Decentralized Scienc…r an IP acquisition — with a participation-gated pro-rata exit (/wiki/governance/voting) sopen to any contributor holding the caper's soulbound vote tokens – minted at 0.01 per XRD of gross value on a buy as well as 1 per ranked ballot, so a backer who never votes still qualifies – letting contributors who lose conviction can withdraw their share rather th… (/wiki/desci/desci-funding) .

Overview Decentralized Scienc…dao) ) – all ten covered here. The listing is not the whole cohort: DermaLabs (/wiki/desci/ecosystem/dermalabs) came off the same launchpad — its $SKIN Ignition Sale ran in December 2025 and Bio published its own profile of the project (https://www.bio.xyz/blog-posts/every-bathroom-mirror-is-a-laboratory-how-dermalabs-is-rebuilding-skincare-science-from-the-ground-up) in February 2026 — but appears in neither the live listing nor the Internet Archive’s 12 June 2026 capture (http://web.archive.org/web/20260612112102/https://www.bio.xyz/) of it, so a count read off the listing and a count read off the launchpad’s own history differ by one. At DeSci.Berlin in June 2026… (/wiki/desci/desci-funding) .

Overview Decentralized Scienc… blockchains, DAOs (/wiki/daos-governance/concepts/fundamentals/what-is…ial layer” — now coordinates 10+ biotech ten BioDAOs (https://www.bio.xyz/) across longevity, women's health, psychedelics and synthetic biology, counted off its own ecosystem listing on 15 August 2026, having raised over $33M in i…(https://www.bio.xyz/) round (– Binance Labs' first DeSci investment, Nov 2024)ember 2024, both dated on Bio's published timeline. The ten span longevity ( VitaDAO (/wiki/desci/ecosystem/vitadao) ), women's health ( AthenaBIO (/wiki/desci/ecosystem/athenadao) ), psychedelics ( PsyDAO (/wiki/desci/ecosystem/psydao) ), synthetic biology ( ValleyDAO (/wiki/desci/ecosystem/valleydao) ), hair loss ( HairDAO (/wiki/desci/ecosystem/hairdao) ), cryopreservation ( CryoDAO (/wiki/desci/ecosystem/cryodao) ), brain health ( Cerebrum DAO (/wiki/desci/ecosystem/cerebrum-dao) ), rare disease ( Curetopia (/wiki/desci/ecosystem/curetopia) ), Long COVID ( Long COVID Labs (/wiki/desci/ecosystem/long-covid-labs) ) and quantum bio-imaging ( Quantum Biology DAO (/wiki/desci/ecosystem/quantum-biology-dao) ) – all ten covered here. At DeSci.Berlin in June 202… votes in a single interface — the same launcher that issues Bio's BioAgents (/wiki/desci/ecosystem/peptai) — a sign that DeSci's frontier … (/wiki/desci/desci-funding) .

Overview Decentralized Scienc… and, increasingly, payment. - Research data ownership (/wiki/desci/research-data-ownership) — data NFTs, data unions, and Data DAOs that let the people who generate genomic and clinical data keep ownership of it and a share of the value. Why now: the 2025–26 public-fu… (/wiki/desci/desci-funding) .

Overview Decentralized Scienc…s, DAOs (/wiki/daos/concepts/fundamentals/what-is-a-dao) , and token inc… (/wiki/desci/desci-funding) .

Overview Decentralized Scienc…. - Misaligned incentives — the reproducibility crisis (/wiki/desci/reproducibility-crisis) and negative results are under… (/wiki/desci/desci-funding) .

Topic Decentralized Science (D…g (/wiki/desci/desci-funding) (quadratic / retroactive), open publishing & review (/wiki/desci/decentralized-publishing) Reference ethereum.org/desc…ttps://ethereum.org/en/desci/)

Overview Decentralized Scienc… blockchains, DAOs (/wiki/daos/concepts/what-is-a-dao) , and… single grant committee. - Open, credited peer review — Decentralized publishing & peer review (/wiki/desci/decentralized-publishing) — open-access research objects and on-chain attestations that give reviewers reputation and,… (/wiki/desci/desci-funding) .

Overview Decentralized Scienc… and, increasingly, payment. Why now: the 2025–26 public-funding shock DeSci's funding-bottleneck thesis stopped being abstract in 2025. Over the year the U.S. government terminated or froze more than 3,800 NIH and NSF research grants — roughly $3 billion in unspent, already-committed funds (https://www.sciencenews.org/article/nih-nsf-cuts-2025-data) , the NIH alone accounting for nearly 2,500 grants (about $2.3 billion). One analysis found the terminations disrupted roughly 1 in 30 active clinical trials, affecting more than 74,000 enrolled participants (https://www.ajmc.com/view/nih-grant-terminations-disrupt-1-in-30-clinical-trials-impacting-over-74-000-participants) . When the dominant grant pipeline contracts this sharply, community- and token-based funding stops being a novelty and becomes a lifeline — the clearest demand-side tailwind DeSci has had. The 2026 landscape DeSci has …berlin/) it launched OpenLabs, — backed by a fresh $6.9 million round (https://manufacturingchemist.com/bio-protocol-launch-ai-powered-decentralised-ai-platform) — pairing AI-assisted project d… (/wiki/desci/desci-funding) .

Topic Decentralized Science (DeSci) What it is Funding, publishing & governing research on public blockchains via DAOs and token incentives Core primitives IP-NFTs (/wiki/desci/ip-nfts) , DeSci DAOs (/wiki/desci/desci-daos) , novel funding (/wiki/desci/desci-funding) (quadratic / retroactive) Reference ethereum.org/desci (https://ethereum.org/en/desci/)

Overview Decentralized Science (DeSci) is a movement to reform how science is funded, published, and governed using public blockchains, DAOs (/wiki/dao/concepts/what-is-a-dao) , and token incentives. As the Ethereum Foundation's DeSci hub (https://ethereum.org/en/desci/) frames it, the goal is to build public infrastructure for “funding, creating, reviewing, crediting, storing, and disseminating scientific knowledge” — addressing systemic failures of the traditional research system. The problems DeSci targets - Funding bottleneck — grant capital is scarce, slow, and gate-kept; low single-digit acceptance rates push researchers to optimize for grant committees rather than discovery. - Closed-access publishing — publicly-funded results sit behind paywalls, and peer review is opaque and unpaid. - IP lock-up — promising early research stalls in university tech-transfer offices, unable to attract capital or reach the public. - Misaligned incentives — reproducibility and negative results are undervalued because they don't advance careers. Core primitives - IP-NFTs & IP Tokens (/wiki/desci/ip-nfts) — tokenize the legal rights to research so a community can own and fund it. - DeSci DAOs (/wiki/desci/desci-daos) — token holders collectively decide which research to fund and how to commercialize the results. - Novel funding (/wiki/desci/desci-funding) — quadratic funding (https://wtfisqf.com/) , retroactive public-goods funding, and token-curated grants replace the single grant committee. - Open, credited peer review — on-chain attestations give reviewers reputation and, increasingly, payment. The 2026 landscape DeSci has consolidated around a few coordination layers. Bio Protocol (/wiki/desci/ecosystem/bio-xyz) — which describes itself as “DeSci's new financial layer” — now coordinates 10+ biotech DAOs (https://www.bio.xyz/) across longevity, women's health, psychedelics and synthetic biology, having raised over $33M in its BIO Genesis (https://www.bio.xyz/) round (Binance Labs' first DeSci investment, Nov 2024). At DeSci.Berlin in June 2026 (https://cryptobriefing.com/bioprotocol-openlabs-desci-berlin/) it launched OpenLabs, pairing AI-assisted project development with community funding votes in a single interface — a sign that DeSci's frontier is moving from tokenizing IP toward operating the full research workflow on-chain. Relevance to Radix Radix's asset-oriented programming (https://radix.wiki/contents/tech/core-concepts/asset-oriented-programming) is well-suited to DeSci: IP-NFTs (/wiki/desci/ip-nfts) are native resources (not contract state), DAOs benefit from engine-level access rules (https://radix.wiki/contents/tech/core-concepts/access-rules-and-auth-zones) , and complex funding flows compose atomically via transaction manifests (https://radix.wiki/contents/tech/core-protocols/transaction-manifests) . See DeSci on Radix (/wiki/desci/desci-and-radix) . How Caper approaches this A research collective doesn't need a bespoke platform to run the DeSci playbook. A caper (/wiki/foundations/what-is-a-caper) gives any group a bonding-curve (/wiki/markets/bonding-curve) treasury to raise from supporters and a proposal system to direct that treasury toward a lab, a milestone, or an IP acquisition — with a participation-gated pro-rata exit (/wiki/governance/voting) so contributors who lose conviction can withdraw their share rather than being locked in. It's the same “community funds the science, community governs the outcome” loop that DeSci pioneered, without a research group having to deploy its own contracts. See DeSci funding (/wiki/desci/desci-funding) .