How Caper approaches this Pum…ferable proof-of-vote token – one perearned by casting ranked ballot casts, and none at all for buying o…). A member's on-chain weight is compute_vote_weight = (t·v)/(V·T) in contracts/common/src/lib.rs –combines their token holdings timeswith their earned votes, over the totals – and that same weight sets eac…s/leaving-a-caper) redemption before the vote tokens are burned. The honest read is that eac… cash out of the consequences.

Name Pump.science (RIF, URO) …ence (DeSci) funding platform —– a tokenized-experiment launch…picin) and $URO (Urolithin A) —– one token per compound under …nologies (FlyBox, fruit flies)

Overview Pump.science is a So… open market decide by buying —– and it wires that market directly to a bench experiment.

How a compound becomes a trade…eployed live on Pump Science" —– the trading interest has clea…itics note the obvious hazard —– the same loop rewards hype ov…t evidence about the compound.

RIF and URO: the first two exp…ber 2024 and spiked violently —– on 18 November 2024, RIF's to…it would focus on RIF and URO —– running mouse experiments bef…obscure geroscience overnight —– and how quickly that attention leaves.

Tokens, IP rights, and the BIO…s a claim on a research asset —– a design that borrows the IP…n a deliberative DAO treasury.

Is Pump.science a DAO? Not in…his reference says so plainly —– much as it does for Research…rol community-funded research.

How Caper approaches this Pum…es almost all of it tradeable —– a compound gets funded when i…nsferable proof-of-vote token —– one per ranked ballot cast, a…nal, and locked to its holder —– its deposit authority is the …n contracts/common/src/lib.rs —– their token holdings times th…earned votes, over the totals —– and that same weight sets eac…uid, permissionless attention —– its whole thesis is that an o… cash out of the consequences.

The lab layer: WormBot and Fly…ical describes the WormBot as "a high-throughput robotics platform combined with neural net AI to perform high-throughput health and survival analysis in worms," feeding a broader effort to screen compounds for lifespan extension at scale ( Ora Biomedical (https://orabiomedical.com/science/) )system that “combines robotics, computer vision and machine learning to test thousands of compounds for their effect on lifespan in C. elegans”, and gives its reason for the animal: a lifespan experiment in C. elegans finishes in about three weeks, which is short enough to repeat at library scale ( Ora Biomedical (https://orabiomedical.com/platform/) , read 21 September 2026). That page puts numbers on the screen behind Pump.science’s two tokens. Ora reports about 10,000 compounds tested on the platform and roughly 1m observations. In the one library it breaks out, 3,794 distinct treatments across 208 runs produced 4,879 conditions, each normalised to its own control, of which 535 extended median lifespan by 20% or more: an 11% hit rate, at a median gain of 30% among the hits. Alongside it Ora cites DrugAge (https://genomics.senescence.info/drugs/) , the public compendium of published lifespan results, at 1,046 compounds across all 35 species it covers and 700 in C. elegans. This layer is why holders r…the honest limit of the model —– worm and fly lifespan screens… from a human longevity claim.

Where RIF and URO stand now Both tokens still trade, and the distance they have fallen is the clearest measure of what the model actually funded. Read from Dexscreener'’s public API (https://api.dexs…/dex/search?q=Rifampicin) on 13 August21 September 2026, against the November 20…ov 2024) Fully diluted value (13 Aug21 Sep 2026) Change 24h volume 24h trades Pooled liquidity $RIF (https://dexscreener.c… (rifampicin) ~$227,000,000 ~$168241,000 -99.893% ~$1744,200 113 buys / 127 sells ~$199,000 $URO (https://dexscreener.c…urolithin A) ~$112,000,000 ~$1581,000 -99.874% ~$182 The volume column is the one to read twice. The Raydium pair for $RIF recorded 15 buys and 14 sells in the twenty-four hours to 13 August 2026, on roughly $174 of turnover across a pool holding about $123,000 of liquidity. Both tokens are, in market terms, dormant - they have a price because liquidity is still parked against them, not because anyone is trading the science. That is t2,400 110 buys / 107 sells ~$149,000 Each row sums the two Raydium pools that hold almost all of that token: one quoted in SOL, which carries most of the depth, and a smaller one quoted in BIO, opened on 30 June 2025 – the BIO Protocol tie described above, expressed as a trading pair. $RIF’s SOL pool holds about $181,000 and turned over $2,462 in the day to the reading; its BIO pool holds about $18,000 and turned over $1,743, so 9% of the depth carried 41% of the volume. This page previously recorded a 13 August 2026 reading of the SOL pool alone – 15 buys and 14 sells on about $174 – and concluded that both tokens were dormant. That conclusion no longer holds, and two different things moved. The SOL pool itself went from 29 trades a day to 127 and from a fully diluted value of about $168,000 to $241,000; and the earlier reading counted one of two pools, so the BIO pair’s turnover was missing from it on both dates. About 460 trades a day now cross the four pools, on turnover of roughly $6,600. A single dated snapshot of one venue settles a liveness question no better here than the repository freshness reading on bonding curve (/wiki/markets/bonding-curve) settles one there. The structural risk of speculation-as-grant-committee stated as a number rathurvives the correction, and is narrower than a wdorrymancy verdict. The funding event is instant…he research is not: a compound'’s token clears its threshold, …e market that commissioned it has moved on long before survival curves come backtakes on no further obligation to it. A treasury (/wiki/dao-gover…nt out of live trading demand does not get a second round from an audience that left. Nothing here says the compounds were the wrong ones, andis left with whatever demand remains. Both tokens sit above the $10,000 market-cap bar the plab layer (https://orabiomedical.com/science/) is unaffected by a token's price - the point is narrower: attention was the funding, and attention has a shorter half-life than a research programmetform uses to commission an experiment, and the nine-figure inflow that made the model famous has gone, so a new compound token would have to raise its own. The platform itself is stil…, not an outage), so this page'’s status reflects the on-chain…r than a claim about the site.

How Caper approaches this Pum…e per ranked ballot cast, and 0.01 per XRD of gross value on each leg of a tradenone at all for buying or selling (fractional, and locked to it… cash out of the consequences.

How Caper approaches this Pum…e allocation mechanism. Caper deliberately removeputs the decisive slice from the market: voting obeyond resale: taking part in a caper mints a soulbound, n…nsferable proof-of-vote token — one per ranked ballot cast, and 0.01 per XRD of gross value on each leg of a trade (fractional, and locked to its… cash out of the consequences.

How Caper approaches this Pum…sferable proof-of-vote token (indivisiblefractional, and locked to its holder — i… cash out of the consequences.

How Caper approaches this Pum…ts each member's exit (/wiki/governance/proposalsfoundations/leaving-a-caper) redemption before the vote … cash out of the consequences.

How Caper approaches this Pum…ht = (t·v)/(V·T) in contracts/logiccommon/src/lib.rs — their token hold… cash out of the consequences.

Where RIF and URO stand now B…ttps://dexscreener.com/solana/gjtjuwd9qyccrkwmbmty1tpapv1skfb2zuv9q4aqpumpa8inixg97ajk5kcxtdi5oodg2drkeebpnw2ghchpe4j1) (rifampicin) ~$227,000,000 …ttps://dexscreener.com/solana/fvgqhmfl9yn39v79hudpy3yundoyjpulwng2jfmqpump3hsdbmfsich3ycsxofjgx4tvpxecsue9nrmgvaoyveqt) (urolithin A) ~$112,000,000…r than a claim about the site.

Where RIF and URO stand now Both tokens still trade, and the distance they have fallen is the clearest measure of what the model actually funded. Read from Dexscreener's public API (https://api.dexscreener.com/latest/dex/search?q=Rifampicin) on 13 August 2026, against the November 2024 peaks reported at the time: Token Peak market cap (18 Nov 2024) Fully diluted value (13 Aug 2026) Change 24h volume $RIF (https://dexscreener.com/solana/gjtjuwd9qyccrkwmbmty1tpapv1skfb2zuv9q4aqpump) (rifampicin) ~$227,000,000 ~$168,000 -99.93% ~$174 $URO (https://dexscreener.com/solana/fvgqhmfl9yn39v79hudpy3yundoyjpulwng2jfmqpump) (urolithin A) ~$112,000,000 ~$151,000 -99.87% ~$182 The volume column is the one to read twice. The Raydium pair for $RIF recorded 15 buys and 14 sells in the twenty-four hours to 13 August 2026, on roughly $174 of turnover across a pool holding about $123,000 of liquidity. Both tokens are, in market terms, dormant - they have a price because liquidity is still parked against them, not because anyone is trading the science. That is the structural risk of speculation-as-grant-committee stated as a number rather than a worry. The funding event is instantaneous and the research is not: a compound's token clears its threshold, the experiment is commissioned, and the market that commissioned it has moved on long before survival curves come back. A treasury (/wiki/dao-governance/concepts/treasury/dao-treasury-management) that raised into the spike keeps the capital; a mechanism that funds each experiment out of live trading demand does not get a second round from an audience that left. Nothing here says the compounds were the wrong ones, and the lab layer (https://orabiomedical.com/science/) is unaffected by a token's price - the point is narrower: attention was the funding, and attention has a shorter half-life than a research programme. The platform itself is still up. pump.science (https://pump.science) answers behind a Vercel bot checkpoint (HTTP 429 to an automated request, not an outage), so this page's status reflects the on-chain reading rather than a claim about the site.

Name Pump.science (RIF, URO) Type Decentralized-science (DeSci) funding platform — a tokenized-experiment launchpad, not a token-voting DAO Focus Financing longevity / healthspan research by turning individual compounds into openly tradeable tokens whose market attention pays for real lab experiments Chain Solana Tokens $RIF (Rifampicin) and $URO (Urolithin A) — one token per compound under study Launched November 2024 (a spin-off of the pump.fun memecoin launchpad) Backers Founded by Paul Kohlhaas, founder/CEO of Molecule (/wiki/desci/ecosystem/molecule) / BIO Protocol (/wiki/desci/ecosystem/bio-xyz) Lab partners Ora Biomedical (WormBot, C. elegans) and Tracked Biotechnologies (FlyBox, fruit flies)

Overview Pump.science is a Solana-based protocol that finances decentralized-science (/wiki/desci/what-is-desci) research into longevity compounds by gamifying the funding step. It is a spin-off of the memecoin launchpad pump.fun (https://pump.fun) : instead of launching a joke coin, a researcher launches a token that stands for a specific real-world compound, and the trading demand for that token pays for the compound to actually be tested in a lab ( Unchained (https://unchainedcrypto.com/decentralized-science-jumps-54-led-by-vitadao-as-well-as-pump-sciences-rif-and-uro/) ). It launched in November 2024 and its first two experiments, $RIF and $URO, briefly became two of the most-watched tokens in crypto, drawing wide attention to DeSci (/wiki/desci/desci-daos) as a category. Pump.science matters to a DAO reference because it is the sharpest live example of a funding model the rest of the field treats cautiously: market speculation as the grant committee. Where a research DAO like VitaDAO (/wiki/desci/ecosystem/vitadao) deliberates over which projects to fund, Pump.science lets an open market decide by buying — and it wires that market directly to a bench experiment.

How a compound becomes a tradeable experiment The pipeline is deliberately simple. A compound is issued as a token on pump.fun's bonding curve (/wiki/markets/bonding-curve) . According to founder Paul Kohlhaas, once a compound's token crosses a $10,000 market cap, "the experiment data is deployed live on Pump Science" — the trading interest has cleared the (very low) bar to fund a real trial, and results then stream back against the token ( Unchained (https://unchainedcrypto.com/decentralized-science-jumps-54-led-by-vitadao-as-well-as-pump-sciences-rif-and-uro/) ). Because a single automated experiment costs on the order of $300, even a modest speculative market can bankroll a full run. The result is a feedback loop unlike anything in traditional grant funding: attention becomes capital, capital becomes an experiment, and the experiment's data feeds back to the people holding the token. Its critics note the obvious hazard — the same loop rewards hype over rigor, and a compound's token price is not evidence about the compound.

RIF and URO: the first two experiments $RIF represents rifampicin (https://en.wikipedia.org/wiki/Rifampicin) , an antibiotic being screened for whether it slows aging in model organisms; $URO represents urolithin A (https://en.wikipedia.org/wiki/Urolithin_A) , a pomegranate-derived compound studied for cellular "clean-up" (mitophagy). Both launched in November 2024 and spiked violently — on 18 November 2024, RIF's token reached roughly a $227M market cap and URO around $112M, each up tens of thousands of percent over the prior week ( Unchained (https://unchainedcrypto.com/decentralized-science-jumps-54-led-by-vitadao-as-well-as-pump-sciences-rif-and-uro/) ). Those valuations then fell sharply from their peaks, and the team said it would focus on RIF and URO — running mouse experiments before introducing any new compound tokens, and pausing further launches until security audits of the application and smart contracts were complete ( ChainCatcher (https://www.chaincatcher.com/en/article/2154094) ). The episode is now a standard case study in how a gamified funding mechanism can pull enormous capital and attention into obscure geroscience overnight — and how quickly that attention leaves.

The lab layer: WormBot and FlyBox What separates Pump.science from a pure memecoin is that the experiments are real and outsourced to specialist labs. Compounds are screened in worms (C. elegans) at Ora Biomedical on its WormBot, and in fruit flies at Tracked Biotechnologies on its FlyBox ( Unchained (https://unchainedcrypto.com/decentralized-science-jumps-54-led-by-vitadao-as-well-as-pump-sciences-rif-and-uro/) ). Ora Biomedical describes the WormBot as "a high-throughput robotics platform combined with neural net AI to perform high-throughput health and survival analysis in worms," feeding a broader effort to screen compounds for lifespan extension at scale ( Ora Biomedical (https://orabiomedical.com/science/) ). This layer is why holders receive something other than price action: standardized survival-curve data on the compound their token names. It is also the honest limit of the model — worm and fly lifespan screens are early, exploratory signals, several translational steps removed from a human longevity claim.

Tokens, IP rights, and the BIO connection Pump.science's tokens are pitched as more than speculation: they "represent real-world intellectual property (/wiki/desci/ip-nfts) governance rights to the underlying compounds' data and to the experiments being traded" ( Unchained (https://unchainedcrypto.com/decentralized-science-jumps-54-led-by-vitadao-as-well-as-pump-sciences-rif-and-uro/) ). That threads the platform into the wider Molecule (/wiki/desci/ecosystem/molecule) / BIO Protocol (/wiki/desci/ecosystem/bio-xyz) ecosystem, since founder Paul Kohlhaas leads both. On 25 December 2024, BIO Protocol announced it would airdrop 50 million BIO tokens proportionally to existing RIF and URO holders, pending governance approval to bridge BIO to Solana ( Bitget News (https://www.bitget.com/news/detail/12560604452292) ). So the token a speculator buys nominally carries a claim on a research asset — a design that borrows the IP-NFT (/wiki/desci/ip-nfts) logic Molecule pioneered for VitaDAO (/wiki/desci/ecosystem/vitadao) , but delivers it through a freely tradeable, meme-launchpad token rather than a deliberative DAO treasury.

Is Pump.science a DAO? Not in the token-voting sense, and this reference says so plainly — much as it does for ResearchHub (/wiki/desci/ecosystem/researchhub) . Pump.science is a funding platform and market, not a governed organization: there is no proposal-and-vote treasury steering the protocol, and the decisive mechanism is a price crossing a threshold, not a member vote. Its tokens confer nominal IP-governance rights over specific experiments, but "which compound gets funded" is decided by open-market buying, not by governance. It earns a place in the DAO-industry directory precisely as the boundary case: the point where DeSci funding (/wiki/desci/desci-funding) stops looking like a DAO and starts looking like a prediction-and-speculation market wired to a lab bench. That makes it the most useful contrast in the BioDAO (/wiki/desci/desci-daos) set for thinking about who should actually control community-funded research.

How Caper approaches this Pump.science and Caper (/wiki/foundations/what-is-a-caper) sit at opposite poles of one question: how much of a community-funded effort's steering should be for sale. Pump.science makes almost all of it tradeable — a compound gets funded when its freely transferable token clears a market-cap bar, so buying pressure is the allocation mechanism. Caper deliberately removes the decisive slice from the market: voting on a caper mints a soulbound, non-transferable proof-of-vote token (indivisible, and locked to its holder — its deposit authority is the component itself, with updates permanently denied, per contracts/core/src/caper_dao.rs). A member's on-chain weight is compute_vote_weight = (t·v)/(V·T) in contracts/logic/src/lib.rs — their token holdings times their earned votes, over the totals — and that same weight sets each member's exit (/wiki/governance/proposals) redemption before the vote tokens are burned. The honest read is that each optimizes for something real. Pump.science maximizes liquid, permissionless attention — its whole thesis is that an open market can fund obscure science faster than any committee. Caper's earned, un-sellable weight is built for the opposite case: when you specifically do not want who-decides to be purchasable, and you want the people steering to be the ones who can't simply cash out of the consequences.