How Caper approaches this Cerebrum shows both the promise and the tension in token-governed research funding. The promise is real:lets a community, notrather than a single fund, decides which neuroscience gets backed, and the community owns the resulting IP-NFTs. The tension iswo features of its governance limit that. NEURON is a freely-tradeable token – so control over which science gets funded has a spot price. A large enough buyer can accumulate NEURON trades freely, so a buyer who accumulates enough of it cand tilt the funding pipeline, and the voicewhich research gets funded, and a long-time contributor earned i's say counts wforth exactly the same as no more than the same balance bought yesterday. Caper (/wiki/foundations/what-is-a-caper) keeps token-weighted stake but adds a factor that cannot be bought off another holder. Every ranked ballot mints a soulbound proof-of-vote token And only three addresses can open a proposal, so a NEURON holder can vote on the pipeline but cannot add to it. A caper (/wiki/foundations/what-is-a-caper) differs on both. Any holder of a caper's token can open a proposal (/wiki/governance/proposals) by paying a fee. A member's say counts two things: the caper's tokens they hold, and thate ballot is the only member-facing way to mint one – buys and sells mint none – non-transferable and fractional (DIVISIBILITY_MAXIMUM, and mintable/depositable only by the DAO component so it can never move between holders; contracts/core/src/caper_dao.rs). A member's voting weight combines held governance tokens with their earned vote record, and the same weight setsy have cast. The ballots sit in a soulbound token (/wiki/dao-governance/concepts/membership/soulbound-tokens) that a member earns only by voting and cannot sell, send or delegate; buying or selling the caper's token earns none. The same measure sets a member's share of their treasury when they exit (/wiki/dao-governance/concepts/membership/rage-quit-and-exit-rights) share. So a big NEURON-style bag still counts, but it cannot by itself capture the pipeline: the decisive part of governance weight is a record you accumulate only by voting yourself, and once minted it can never be sold onfoundations/leaving-a-caper) . A large holding still counts, but it is one of two inputs, and nobody can buy the other from a member, so a big bag alone can't capture which research gets funded.

How Caper approaches this Cer…er. Every ranked ballot mints onea soulbound proof-of-vote token…rs). A member's voting weight is (t·v)/(V·T) –combines held governance tokens t multiplied bywith their earned vote record v, over supply – and, and the same weight sets their treasury exit (/wiki/dao-gov…e-quit-and-exit-rights) share is computed by the very same formula. So a big NEURON-style bag still counts (t is a multiplier, not ignored), but it cannot by itself capt…inted it can never be sold on.

Type BioDAO —– neuroscience / brain-health r…ken NEURON (ERC-20, Ethereum) —– governance + IP-NFT access L…(https://www.cerebrumdao.com/)

Cerebrum DAO is a Bio Protoco…s area is Alzheimer's disease —– a condition it notes affects …her than a single lab or fund.

What Cerebrum DAO funds Cereb…unction, and vascular changes —– with particular attention to …iki/desci/ecosystem/vitadao) —– funding research before a com… on-chain claim on its upside.

The IP-NFT portfolio As of mi…mmation (Dr Maryna Polyakova) —– $50,000 Xponetiq Mobile app …om/projects/percepta-brain) ) —– an illustration of how a BioD…y rather than a whole company.

How Caper approaches this Cer…N is a freely-tradeable token —– so control over which science…member-facing way to mint one —– buys and sells mint none —– non-transferable and fraction… voting weight is (t·v)/(V·T) —– held governance tokens t mult…ed vote record v, over supply —– and the treasury exit (/wiki…inted it can never be sold on.

The governance record The ce… a ballot but cannot open one.Two of those three addresses w…esign) cannot fix on its own.

The IP-NFT portfolio As of mi…ww.cerebrumdao.com/projects) ):. Read again on 27 September 2026, the same page still shows $1.3 million across seven investments and more than 150 projects evaluated, beside a live treasury figure of $1,689,366. Project What it is Instrumen…y rather than a whole company.

The governance record The ce…e when the record was queried again on 27 September 2026, so the gap ru…t a ballot but cannot open one –. Two of those three addresses wrote all twenty proposals, thirteen from the space's one listed member and seven from an admin, starting with CDP-1, the governance framework, on 23 April 2024 ( Snapshot hub (https://hub.snapshot.org/graphql) , read 27 September 2026). That is the pattern this wiki measure…esign) cannot fix on its own.

How Caper approaches this Cer…ound proof-of-vote token, and every buy and every sell mints 0.01 more per XRD of gross valuthat ballot is the only member-facing way to mint one — buys and sells mint none — non-transferable and fract…ht is a record you accumulate by trading andonly by voting yourself, and once minted it can never be sold on.

The governance record The ce…st recent proposal of any kind, which puts the space 230 days without a vote as of 18 August 2026: it was still the newest row in the cerebrumdao.eth (https://snapshot.box/#/s:cerebrumdao.eth) space when the record was queried on 2 September 2026, so the gap runs from its close on 31 December 2025. It is dated from that close rather than published as an elapsed-day figure, which would be wrong the day after it was written. Proposal creation is restric…esign) cannot fix on its own.

How Caper approaches this Cer…a factor that cannot be bought. Every v off another holder. Every ranked ballote mints aone soulbound proof-of-vote token, and every buy and every sell mints 0.01 more per XRD of gross value — non-transferable and fracti…ure the pipeline: the decisive, earned part of governance weight is a record you accumulate by participating, and it is not for saletrading and voting yourself, and once minted it can never be sold on.

How Caper approaches this Cer… token — non-transferable and indivisiblefractional (DIVISIBILITY_NONEMAXIMUM, and mintable/depositable onl…ating, and it is not for sale.

NEURON token & governance Cer…om/neuron-token) ). Voting is ontoken-weighted but off-chain, and token-weighted: influence ovhe DAO's own site says where: every governance link on cerebrumdao.com (https://www.cerebrumdao.com/neuron-token) points at the Snapshot space cerebrumdao.eth (https://snapshot.box/#/s:cerebrumdao.eth) , where a ballot is a signed message rather than a transaction. Weight is not raw balance either: the funding pipeline scales with the size of a holder's NEURON balspace runs two strategies, a with-delegation wrapper over erc20-balance-of so delegated NEURON counts for the delegate, and a sablier-v2 strategy on the reserved recipient of a stream, so NEURON still vesting counts for the person it is vesting to. The distinction between signing and transacting is the subject of on-chain versus off-chain governance (/wiki/dao-governance/concepts/fundamentals/on-chain-vs-off-chain-governance) .

The governance record The cerebrumdao.eth (https://snapshot.box/#/s:cerebrumdao.eth) space has carried 20 proposals against a quorum of 3,870,000,000 NEURON. Read on 18 August 2026, the five most recent all passed unanimously and all cleared quorum comfortably: CDP-20 (https://snapshot.box/#/s:cerebrumdao.eth/proposal/0xa6c1daa414bacfd8ee9b2dd0d16d03c8ca01e97ad789a3950e3395845a94f0c6) , funding dark-microglia and lipidomics work, closed on 31 December 2025 with 7,360,852,054 NEURON For, zero Against and zero Abstain from twelve voting addresses; CDP-19 drew 6,879,399,526 from sixteen, CDP-18 6,213,626,585 from thirteen, CDP-17 9,471,106,026 from twelve and CDP-16 6,639,917,945 from sixteen. Not one of the five recorded a single vote against. CDP-20 is also the most recent proposal of any kind, which puts the space 230 days without a vote as of 18 August 2026. Proposal creation is restricted to an author allowlist of three addresses, so a NEURON holder can cast a ballot but cannot open one – the pattern this wiki measures across the whole BioDAO cohort under proposal throttles and rate limits (/wiki/dao-governance/concepts/voting/proposal-throttles-and-rate-limits) , where ten of twelve DeSci spaces gate proposing the same way. Twelve to sixteen voters and no dissent across two years is a small electorate ratifying a pipeline it did not assemble, which is the shape voter apathy (/wiki/dao-governance/concepts/analysis/voter-apathy) describes and quorum design (/wiki/dao-governance/concepts/voting/quorum-and-threshold-design) cannot fix on its own.

How Caper approaches this Cer…ve between holders; contracts/core/src/caper_dao.rs). A member's … the treasury exit (/wiki/daos-governance/concepts/membership/rage-quit…ating, and it is not for sale.

How Caper approaches this Cer…ry exit (/wiki/daos/concepts/membership/rage-quit-and-exit-rights) sh…ating, and it is not for sale.

Cerebrum DAO is a Bio Protoco…in as an IP-NFT (/wiki/desci/concepts/ip-nfts) owned by the communi…her than a single lab or fund.

How Caper approaches this Cer…and the treasury exit (/wiki/governancedaos/concepts/rage-quit-and-exit-rights) s…ating, and it is not for sale.

Type BioDAO — neuroscience / brain-health research funding Focus Extending healthy brain lifespan; first target Alzheimer's disease and neurodegeneration Founder Brian Magierski (also founder of 21 Impact Labs, CEO of Xponetiq) Token NEURON (ERC-20, Ethereum) — governance + IP-NFT access Launched NEURON Dutch auction on the Bio Protocol (/wiki/desci/ecosystem/bio-xyz) launchpad, deadline 30 April 2024 Portfolio ~$1.3M committed across 7 projects (IP-NFT, IP-license and equity deals) IP framework Molecule (/wiki/desci/ecosystem/molecule) IPNFT protocol Website cerebrumdao.com (https://www.cerebrumdao.com/)

Cerebrum DAO is a Bio Protocol (/wiki/desci/ecosystem/bio-xyz) BioDAO that, in its own words, is "a community-powered network organization to source, fund, and translate research that accelerates solutions to extend healthy brain lifespan" ( cerebrumdao.com/about (https://www.cerebrumdao.com/about) ). Its first focus area is Alzheimer's disease — a condition it notes affects some 6.7 million Americans, with cases projected to rise sharply by 2050 ( Bio Protocol (https://www.bio.xyz/blog-posts/bringing-neuroscience-onchain-with-cerebrum-dao) ). Founder Brian Magierski has said the effort was motivated by his daughter's Down syndrome diagnosis, which carries a near-certain lifetime risk of Alzheimer's dementia. Cerebrum follows the VitaDAO (/wiki/desci/ecosystem/vitadao) model pioneered across the Bio Protocol pipeline: a freely-tradeable governance token funds early-stage translational research, and the resulting intellectual property is tokenized on-chain as an IP-NFT (/wiki/desci/concepts/ip-nfts) owned by the community rather than a single lab or fund.

What Cerebrum DAO funds Cerebrum treats neurodegeneration as tightly coupled to biological aging, and concentrates on the upstream drivers of brain decline: neuro-inflammation, metabolic stress, mitochondrial dysfunction, and vascular changes — with particular attention to blood-brain-barrier dysfunction ( cerebrumdao.com (https://www.cerebrumdao.com/) ). Researchers apply for funding directly, with a stated 6–8 week response window depending on the pipeline ( cerebrumdao.com/researchers (https://www.cerebrumdao.com/researchers) ). When the DAO backs a project, the IP is tokenized "using the IPNFT protocol, ensuring equitable distribution of license and governance rights," and licensing proceeds are split between the researchers and the DAO ( cerebrumdao.com/about (https://www.cerebrumdao.com/about) ). This is the same Molecule (/wiki/desci/ecosystem/molecule) -built mechanism used by HairDAO (/wiki/desci/ecosystem/hairdao) and VitaDAO (/wiki/desci/ecosystem/vitadao) — funding research before a company exists and giving the community an on-chain claim on its upside.

The IP-NFT portfolio As of mid-2026 Cerebrum reports roughly $1.3 million committed across seven projects ( cerebrumdao.com/projects (https://www.cerebrumdao.com/projects) ): Project What it is Instrument Allocated Fission Bio (https://www.cerebrumdao.com/projects/fission-bio) Protein–protein interaction inhibitor severing the link between chronic inflammation and mitochondrial dysfunction IP-Token $400,000 Percepta® (https://www.cerebrumdao.com/projects/percepta-brain) Patent-protected brain-health supplement (PTI-00703® cat's claw + MemorTea® oolong extract); tokenized as IP-NFT #129 (https://etherscan.io/nft/0xcaD88677CA87a7815728C72D74B4ff4982d54Fc1/129) IP Portfolio License $400,000 Project Transfidelity (https://www.cerebrumdao.com/projects/project-transfidelity) Enhancing protein-translation fidelity to combat neurodegeneration (Dr Dimitri Scherbakov, University of Zurich) IP-Token $254,000 Arctic Therapeutics (AT-001) Oral NAC-amide (NACA) disrupting amyloid plaques; Phase IIa data in HCCAA patients (Dr Hakon Hakonarson) Equity €75,000 SK-Channels Small-molecule modulator for tremors and ataxia IP License $60,000 Neuron-Gale Galectin-3 inhibitors for neuro-inflammation (Dr Maryna Polyakova) — $50,000 Xponetiq Mobile app for brain-healthy habits Product $50,000 Cerebrum describes the Percepta deal as "a world's first tokenization of a robust patent portfolio and a world's first tokenized crowdsale for a clinical evidence study" ( cerebrumdao.com (https://www.cerebrumdao.com/projects/percepta-brain) ) — an illustration of how a BioDAO can pool retail capital behind a specific clinical study rather than a whole company.

NEURON token & governance Cerebrum raised its treasury through a Dutch auction of the NEURON token on the Bio Protocol (/wiki/desci/ecosystem/bio-xyz) launchpad, with a deadline of 3pm CET on 30 April 2024; every participant paid the same clearing price and lower bidders were refunded, with US persons excluded and Persona KYC required ( Bio Protocol (https://www.bio.xyz/blog-posts/bringing-neuroscience-onchain-with-cerebrum-dao) ). NEURON is a freely-transferable ERC-20 on Ethereum ( 0xab81…4a6b (https://etherscan.io/token/0xab814ce69e15f6b9660a3b184c0b0c97b9394a6b) ). Holding NEURON confers governance rights over which research the DAO funds, plus exclusive access to the DAO's IP Tokens, discounted access to future brain-health products, and early access to any therapeutics it brings to market ( cerebrumdao.com/neuron-token (https://www.cerebrumdao.com/neuron-token) ). Voting is on-chain and token-weighted: influence over the funding pipeline scales with the size of a holder's NEURON balance.

How Caper approaches this Cerebrum shows both the promise and the tension in token-governed research funding. The promise is real: a community, not a single fund, decides which neuroscience gets backed, and owns the resulting IP-NFTs. The tension is that NEURON is a freely-tradeable token — so control over which science gets funded has a spot price. A large enough buyer can accumulate NEURON and tilt the funding pipeline, and the voice a long-time contributor earned is worth exactly the same as the same balance bought yesterday. Caper (/wiki/foundations/what-is-a-caper) keeps token-weighted stake but adds a factor that cannot be bought. Every vote mints a soulbound proof-of-vote token — non-transferable and indivisible (DIVISIBILITY_NONE, and mintable/depositable only by the DAO component so it can never move between holders; contracts/src/caper_dao.rs). A member's voting weight is (t·v)/(V·T) — held governance tokens t multiplied by their earned vote record v, over supply — and the treasury exit (/wiki/governance/rage-quit-and-exit-rights) share is computed by the very same formula. So a big NEURON-style bag still counts (t is a multiplier, not ignored), but it cannot by itself capture the pipeline: the decisive, earned part of governance weight is a record you accumulate by participating, and it is not for sale.